Hairy Cell Leukemia in a Young Male: An Unusual Presentation
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Abstract:
Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and hepatomegaly (liver span - 16.9 cm). However, no lymphadenopathy was found.
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hairy cell leukemia in a young male: an unusual presentation
dear editor-in-chief a 28 yr male was presented in october 2015 at medicine outpatient department, safdarjung hospital, new delhi- india with generalized weakness, fever and cough for preceding 15 days. clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and hepatomegaly (liver span - 16.9 cm). however, no lymphadenopathy was found.
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Hairy cell leukemia is an indolent, chronic B-cell lymphoproliferative disorder comprising approximately 2 to 3% of all adult leukemias in the United States. Hairy cells are clonal expansions of mature, activated B-cells. They co-express CD11c, CD19, CD20, CD22, CD25, and CD103. Hairy cells possess clonal immunoglobulin gene rearrangements and express monoclonal surface immunoglobulin of either...
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Journal title
volume 11 issue 4
pages 421- 422
publication date 2016-10-01
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